Upper airway biopsy

定义

Upper airway biopsy is surgery to remove a small piece of tissue from the nose, 口, 喉部面积. The tissue will be examined under the microscope by a pathologist.

选择的名字

Biopsy - upper airway

How the Test is Performed

The health care provider will spray a numbing medicine in your 口 and throat. A metal tube is inserted to hold your tongue out of the way.

Another numbing medicine flows through the tube down the back of the throat. This may cause you to cough at first. When the area feels thick or swollen, it is numb.

The test may also be performed under general anesthesia, so that you will be asleep and not feel pain.

The provider looks at the abnormal area, and removes a small piece of tissue. It is sent to the laboratory for examination.

How to Prepare for the Test

DO NOT eat for 6 to 12 hours before the test.

Tell your provider if you take a blood thinner, 比如阿司匹林, 氯吡格雷, 或华法林, when you schedule the biopsy. You may need to stop taking them for a little while. Never stop taking any medicines without first talking to your provider.

How the Test will Feel

As the area is being numbed, you may feel like there is fluid running down the back of your throat. You may feel the need to cough or gag. And you may feel pressure or mild tugging.

When the numbness wears off, your throat may feel scratchy for several days. After the test, the cough reflex will return in 1 to 2 hours. Then you may eat and drink normally.

Why the Test is Performed

This test may be done if your provider thinks there is a problem with your upper airway. It may also be done with a 支气管镜检查.

正常的结果

The upper airway tissues are normal, with no abnormal growths.

What Abnormal Results Mean

Disorders or conditions that may be discovered include:

• Benign (noncancerous) cysts or masses
• 癌症
• 某些感染
• 肉芽肿 and related inflammation (may be caused by 肺结核)
• Autoimmune disorders, such as granulomatosis with polyangiitis
• Necrotizing vasculitis

风险

风险 for this procedure include:

• Bleeding (some bleeding is common, heavy bleeding is not)
• Breathing difficulties
• 喉咙痛

There is a risk of choking if you swallow water or food before the numbness wears off.

参考文献

Barbareschi M, Mengoli MC, Cavazza A. Nonneoplastic pathology of the large and small airways. In: Smith ML, Leslie KO, Wick MR, eds. Practical Pulmonary Pathology. 第四版. Philadelphia, PA: Elsevier; 2024:chap 9.

梅森JC. Rheumatic diseases and the cardiovascular system. In: Libby P, Bonow RO, Mann DL, Tomaselli GF, Bhatt DL, Solomon SD, eds. Braunwald's Heart Disease: A Textbook of Cardiovascular Medicine. 12日艾德. Philadelphia, PA: Elsevier; 2022:chap 97.

White V, Ruparelia P. 呼吸道疾病. In: Feather A, Randall D, Waterhouse M, eds. Kumar and Clark's Clinical Medicine. 10日艾德. Philadelphia, PA: Elsevier; 2021:chap 28.

Yu DH, Feller-Kopman D. Tracheobronchial endoscopy. In: Flint PW, Francis HW, Haughey BH, et al, eds. Cummings Otolaryngology: Head and Neck Surgery. 7日艾德. Philadelphia, PA: Elsevier; 2021:chap 71.